Pipeline of Innovative Medicines
Our innovative pipeline focuses the power of our platform to address the unmet needs of patients with cancer and inflammatory diseases. Our goal is to empower the body to fight disease using small molecule drugs to activate or inhibit the natural process of protein degradation.
Targeted Protein Degradation
Nurix is at the forefront of a new modality of treating disease: Targeted Protein Degradation. Using our powerful DELigase platform, Nurix is developing a pipeline of innovative small molecules that harness the activity of a class of enzymes called E3 ligases to degrade specific proteins within the cell.
Targeted Protein Elevation
In contrast to Targeted Protein Degraders, which degrade a specific disease-causing protein, ligase inhibitors prevent the degradation and thus raise the level of proteins normally controlled by the target ligase. The ability to turn up or turn down protein levels is a differentiating feature of Nurix’s technology.
Blaze your trail
We are committed to the highest level of scientific inquiry and integrity. Our team is talented and united in our goal to develop innovative medicines to address patients’ unmet medical needs. If you would like to be part of our world-class team and share our exciting journey, we want to hear from you.