Robert Tjian, Ph.D., has served as the Chair of Nurix’s Scientific Advisory Board since October 2020 and was a member of the company’s board of directors from November 2016 through October 2020. Dr. Tjian is currently a Discovery Partner at The Column Group, a healthcare venture capital firm, where he has worked since September 2016. Prior to joining The Column Group, Dr. Tjian served as President of the Howard Hughes Medical Institute from 2009 to September 2016. Prior to that, Dr. Tjian served in a variety of leadership roles as a faculty member at the University of California, Berkeley, including as Director of the Berkeley Stem Cell Center, Faculty Director of the Li Ka Shing Center for Biomedical and Health Sciences, and Head of the Siebel Stem Institute. Dr. Tjian currently holds the Li Ka Shing Chancellor’s Chair in Biology at the University of California, Berkeley and serves as a scientific advisor to the Chan Zuckerberg Initiative and Chan Zuckerberg BioHub. Dr. Tjian holds a B.A. from University of California, Berkeley in Biochemistry and a Ph.D. in Molecular Biology from Harvard University.
John Kuriyan, Ph.D., is an expert in the structural dynamics of ubiquitin ligases and other signaling complexes. Dr. Kuriyan is a Howard Hughes Medical Institute Investigator and a Professor of Molecular and Cell Biology and of Chemistry, University of California, Berkeley. Prior to that, he served as Assistant Professor and then Professor at Rockefeller University for 14 years. Dr. Kuriyan serves as a member of the Advisory Board at Carmot Therapeutics Inc. and is a Senior Editor at eLife, a new enterprise in high profile and open access scientific publishing. He is a member of the National Academy of Sciences, which awarded him the 2005 Richard Lounsbery Award. He holds a B.S. in chemistry from Juniata College, Pennsylvania, and a Ph.D. from the Massachusetts Institute of Technology.
Michael Rapé, Ph.D., is a leader in the biology of ubiquitin-dependent cell cycle progression and carcinogenesis. He is a Howard Hughes Investigator and a Professor of Cell and Developmental Biology at the University of California, Berkeley. He started his own lab at the University of California, Berkeley in the fall of 2006, where he has developed novel screening tools to identify the ubiquitylation enzymes that are important for cell division and differentiation and pair them with the proteins they target. Prior to that, he completed his postdoctoral research at Harvard Medical School in the lab of Marc Kirschner. In recognition of his creativity and productivity, Dr. Rapé was named a Pew Scholar and received the NIH Director’s New Innovator Award in 2007. He has also won prestigious fellowships from the Human Frontier Science Program and the European Molecular Biology Organization. Dr. Rapé studied Biochemistry at the University of Bayreuth in Germany and received his Ph.D. at the MPI in Martinsried, Germany in the lab of Stefan Jentsch.
Cristiana Guiducci, Ph.D., has served as Senior Vice President, Immunology and Oncology Research of Nurix since January 2021 and served as the company’s Vice President, Immunology and Oncology Research from 2019 through 2020. Prior to joining Nurix, Cristiana Guiducci was the Vice President of Oncology Research at Dynavax Technologies where she directed all foundational research leading to the development of the Dynavax immuno-oncology assets. Prior to her work in oncology, she directed the discovery and characterization of drug candidates for autoimmune diseases at Dynavax. She received her bachelor and master’s degrees in molecular biology from University of Rome, Italy and her Ph.D. in immunology from the Open University of London, UK. She completed her post-doctoral training at National Tumor Institute in Milan, Italy.
Robert J. Brown, M.D. has served as Senior Vice President of Clinical Development since January 2021 and served as the company’s Vice President of Clinical Development from June through December 2020. He is trained as a pediatric neuro-oncologist with a decade of immunotherapy drug development expertise. Prior to joining Nurix, Dr. Brown led cellular therapy development programs in both solid tumors and hematologic malignancies, including allogeneic CAR-T cells at Allogene and tumor infiltrating lymphocytes at Iovance Biotherapeutics. Dr. Brown’s training includes pediatric oncology at the Yale School of Medicine and the treatment of pediatric brain and spinal cord tumors at Children’s Hospital Los Angeles and University of Southern California. He completed a postdoctoral fellowship in radiation-induced brain injury at UCLA, focusing on the role of long-term inflammation on brain development, repair, and dementia. He holds a B.Sc. in chemistry from the Massachusetts Institute of Technology and an M.D. from the Weill Cornell Medical College in New York.
Jeffrey Tong, Ph.D., has served as a member of our board of directors since February 2018. Dr. Tong is currently a Partner at Third Rock Ventures, a venture capital firm, where he has worked since May 2016. Prior to joining Third Rock, Dr. Tong served as Executive Chairman of the Board of Delinia, Inc. (acquired by Celgene Corporation in 2017), a biotechnology company focused on autoimmune diseases. Dr. Tong served as President and Chief Executive Officer of Nora Therapeutics Inc. from 2010 to 2015 and was a member of the executive team of Infinity Pharmaceuticals, Inc. from 2001 to 2010. Dr. Tong currently serves as a member of the board of directors of several private companies. Dr. Tong holds an A.B. in Biochemistry from Harvard College, an M.M.S from Harvard Medical School, and an A.M. and Ph.D. in Chemistry from Harvard University.
Jason Kantor, Ph.D. has served as Senior Vice President, Finance and Investment Strategy of Nurix since July 2020. Prior to joining Nurix, Dr. Kantor served as a senior biopharma analyst at Artisan Partners, where he covered industry trends for both large and small cap biotech and pharma companies globally. He also served as board president at Biotech Partners, meeting the non-profit’s goals of increasing corporate sponsorship and gaining support from local government. Dr. Kantor previously served as managing director, biotechnology analyst at Credit Suisse, RBC Capital Markets and WR Hambrecht + Co, focusing on innovative biotech companies and building successful healthcare and research franchises. Prior to that, he held a position as vice president, biotechnology analyst at JP Morgan Chase & Co. Dr. Kantor holds a B.A. in biology from the University of California, San Diego and a Ph.D. in cell and development biology from Harvard University.
Dr. Siegall has served as a member of our board of directors since May 2021. Dr. Siegall currently serves as President, Chief Executive Officer, and Chairman of the Board of Seagen Inc. (formerly Seattle Genetics, Inc.). Dr. Siegall co-founded Seagen in 1998. Prior to co-founding Seagen, Dr. Siegall worked for the Bristol-Myers Squibb Pharmaceutical Research Institute from 1991 to 1997, most recently as a Principal Scientist. From 1988 to 1991, Dr. Siegall was a Staff Fellow/Biotechnology Fellow at the National Cancer Institute, National Institutes of Health. In addition to Seagen, Dr. Siegall served as a director of Ultragenyx Pharmaceuticals, Inc. from January 2014 to June 2021. Dr. Siegall also served as a director of Alder BioPharmaceuticals, Inc. from November 2005 to October 2019 and as a director of Mirna Therapeutics, Inc. from January 2013 to December 2016. Dr. Siegall received a B.S. in Zoology from the University of Maryland and a Ph.D. in Genetics from George Washington University.
Christine Ring, Ph.D., J.D., has served as Secretary of Nurix since March 2020 and as the company’s General Counsel since September 2019. Prior to joining Nurix, Dr. Ring held multiple positions assisting companies protect intellectual property, engage in licensing transactions, raise capital, and transition from private companies into public companies. Her most recent corporate positions were as Senior Vice President, Legal at Dermira, Inc., a biotechnology company focused on medical dermatology, and as Senior Vice President of Technology, Strategy & Licensing at Amyris, Inc., a biotechnology company focused on renewable fuels and specialty chemicals. Dr. Ring holds an A.B. in Biophysics from the University of California, Berkeley, a Ph.D. in Pharmaceutical Chemistry from the University of California, San Francisco, and a J.D. from the University of California, Hastings College of the Law.
Lori A. Kunkel, M.D., has served as a member of our board of directors since July 2019. Dr. Kunkel is a biotechnology consultant at LAK505, LLC (previously D2D, LLC), where she advises on drug development, strategy, and commercialization, a position she has held since 2004. Dr. Kunkel served as Chief Medical Officer of Pharmacyclics LLC from 2011 to 2013 and of Proteolix, Inc. from 2007 to 2009. From 2005 to 2007, Dr. Kunkel served as Vice President of Clinical Development of Xencor, Inc. Dr. Kunkel currently serves on the board of directors of Curis, Inc., Maverick Therapeutics, Inc., and Oric Pharmaceuticals, Inc. and served as a director of Loxo Oncology, Inc. from October 2014 until February 2019 and Tocagen 2015 to 2020. Dr. Kunkel also serves as a scientific advisor to a number of public and private biotechnology companies. Dr. Kunkel received a B.A. in Biology from University of California, San Diego and an M.D. from the University of Southern California.