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  • Inside The Science
    • DEL-AI Discovery Engine
    • Targeted Protein Degradation
    • Resource Library
  • Advancing Our Pipeline
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Presentations

ACR Convergence 2024 Poster
Presentations

NX-5948, a Clinical-Stage BTK Degrader, Achieves Deep Suppression of BCR, TLR, and FcR Signaling in Immune Cells and Demonstrates Efficacy in Preclinical Models of Arthritis and Other Inflammatory Diseases

By webmaster / November 16, 2024
Presentations

IRAK4 Degrader GS-6791 Inhibits TLR and IL-1R-Driven Inflammatory Signaling, and Ameliorates Disease in a Preclinical Arthritis Model

By webmaster / November 15, 2024
Presentations

Clinical Activity of NX-5948: A First-in-Class BTK Degrader

By webmaster / October 30, 2024
Presentations

An Orally Bioavailable, Brain Penetrant, Pan-Mutant BRAF Degrader for the Treatment of Primary and Inhibitor-Resistant Solid Tumors

By webmaster / October 29, 2024
NX-5948--BTK-Degrader-with-Activity-in-Lymphoid-Malignancies-thumb
Presentations

NX-5948: BTK Degrader with Activity in Lymphoid Malignancies

By webmaster / October 19, 2024
Screening-DNA-Binding-Proteins-with-DNA-Encoded-Libraries-thumb
Presentations

Screening DNA Binding Proteins with DNA Encoded Libraries

By webmaster / October 3, 2024
The-Evolving-Chemical-Space-of-Bi-functional-Degraders-Targeting-the-CNS-thumb
Presentations

The Evolving Chemical Space of Bi-functional Degraders Targeting the CNS

By webmaster / October 1, 2024
Rational-Discovery-of-a-Small-Molecule-Intramolecular-Glue-Inhibitor-of-CBL-B-that-Enhances-T-cell-Function-thumb
Presentations

Rational Discovery of a Small Molecule Intramolecular Glue Inhibitor of CBL-B that Enhances T-cell Function

By webmaster / October 1, 2024
Accelerating-Targeted-Protein-Degrader-Discovery-with-Automated-and-Integrated-Direct-To-Biology-Screening-thumb
Presentations

Accelerating Targeted Protein Degrader Discovery with Automated and Integrated Direct-To-Biology Screening

By webmaster / September 10, 2024
Targeted-Protein-Degraders-As-Next-Generation-Antibody-Payloads-thumb
Presentations

Targeted Protein Degraders As Next Generation Antibody Payloads

By AldenMC Production / September 9, 2024
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