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  • Inside The Science
    • DEL-AI Discovery Engine
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    • Resource Library
  • Advancing Our Pipeline
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NX-1607

Small Molecule Inhibition Of The Ubiquitin Ligase CBL-B With NX-1607 Results In Potent T And NK Cell Mediated Anti-Tumor Response

By aterrado@waterhousebrands.com / January 7, 2025

Initial Clinical Characterization Of Novel Proximal Biomarkers For NX-1607, A First-In-Class Oral CBL-B Inhibitor, In Patients With Advanced Malignancies

By aterrado@waterhousebrands.com / January 7, 2025

NX-1607, A Small Molecule Inhibitor Of The CBL-B E3 Ubiquitin Ligase, Promotes T And NK Cell Activation And Enhances NK-Mediated ADCC In A Mouse Lymphoma Tumor Model

By aterrado@waterhousebrands.com / January 7, 2025

NX-1607, A Small Molecule Inhibitor Of CBL-B, Is Efficacious As A Single Agent And In Combination With Rituximab In Preclinical Mouse Models Of Lymphoma

By aterrado@waterhousebrands.com / January 7, 2025

NX-1607, A Small Molecule Inhibitor Of CBL-B, Enhances Anti-PD-1-Mediated Tumor Growth Inhibition By Reshaping Intratumoral Innate And Adaptive Immune Responses

By aterrado@waterhousebrands.com / January 7, 2025

NX-1607: A First-In-Class Inhibitor Of Casitas B-Lineage Lymphoma B (CBL-B) For Immuno-Oncology

By aterrado@waterhousebrands.com / January 7, 2025

Rational Discovery Of A Small Molecule Intramolecular Glue Inhibitor Of CBL-B That Enhances T-Cell Function

By aterrado@waterhousebrands.com / January 7, 2025
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